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We are always “dumb” because our brain neurons are dying. It depends on what the word “dumb”means to you. This means forgetting some knowledge or simply becoming inadequate. And in fact, it's a myth that alcohol kills neurons. It rather interferes with their proper operation by reducing the density of white matter. But with a large use, Wernicke-Korsakov syndrome can occur with a vitamin B1 deficiency, then they will die off. This does not mean that you can drink, it is better not to do it at all. More neurons will die off due to stress