2 Answers

  1. Hello! There are various forms of dementia (vascular dementia, Alzheimer's disease, frontotemporal dementia, Lewy body dementia).
    Some of these forms of dementia have a hereditary predisposition, but 100% of familial forms of the disease do not.
    Let's take a closer look:
    Familial form of Alzheimer's disease
    Cases of this type of Alzheimer's disease are very rare. Today, there are fewer than a thousand families in the world in which the disease is transmitted from parents to children. If one parent is a carrier of the mutated gene, each of their children will have a 50% chance of inheriting the gene. In this case, the external symptoms of Alzheimer's disease, as a rule, begin to develop quite early: after 30 years (non-hereditary forms usually make themselves felt no earlier than 65 years).
    Familial vascular dementia
    As with Alzheimer's disease, vascular dementia caused by a gene mutation is extremely rare. These include, for example, autosomal dominant arteriopathy of the brain with subcortical infarcts and leukoencephalopathy.
    Frontotemporal dementia (LVD)
    Genes play the most prominent role in the genesis of frontotemporal dementia.
    About 10-15% of people with HDL have a strong family history – the presence of at least three relatives with a similar disease in the next two generations.
    Dementia with Lewy bodies
    The genetics of dementia with Lewy bodies (LTL) is the least studied topic. Some authors of a few studies cautiously suggest that the presence of a patient with DTL among the next of kin may slightly increase the risk of developing this type of dementia, but it is too early to draw final conclusions.
    Family cases of dementia with Lewy bodies
    Such cases are known to science. A strict inheritance pattern was identified in several families, but the mutation of the gene responsible for this scheme was never identified.
    In conclusion, I would like to emphasize that despite the importance of genetic factors, the risk of developing dementia in most cases can be reduced by lifestyle, and quite significantly.

  2. Dementia – acquired dementia. The syndrome is characterized by the breakdown of mental functions resulting from disease or damage to the brain after its maturation is complete

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