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First of all, there are nerves in the head. The brain is made up of them. But the brain itself can't really hurt.
The source of headache is a thin film covering the outer surface of the brain. This film is saturated with blood vessels that feed the thickness of the brain, and very delicate nerve endings. Slight stretching or compression of this film, for example, as a result of changes in blood pressure or vascular tone, and leads to headaches.