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hmmm, it seems to me that not everything is so simple with spayspami.
for example, there is a drug called reagent, it is bodyazhat in alcohol or acetone and sprayed with simple grass, and it turns out that cannabis is also only more powerful, well, it depends on the reagent, and how to bodyazhit it so as not to overdo it, the dealers already know, so everything is normal here. but here's the spice.
I think I should add that the effect of CBD prevents the occurrence of psychoses and hallucinations, and there is no CBD in synthetics. it is also important to add that spice is not just a herb sprayed with a cannabinoid, but also the herb itself sometimes has a galutsenogenic effect. plus, no one writes on spice how it was bodyazhili, what reagent, but on sites where they buy spice there is information that you need to smoke in doses of 5-50mg maximum, so figure it out, 3000mg is 3g of spice, that is, it should be smoked at least 60 times, who did it and when? hence all the troubles, I think this is the essence of insanity with an overdose of spice, because when you smoke grass soaked only with a synthetic cannabinoid or reagent, the effect is ideally reminiscent of coming from a powerful sativa, let's say, or a powerful hash, and there are no glitches or psychoses, and in general you can safely drink coffee in a cafe, for example, getting high only with reagent.
in general, if you want to smoke spice, then first eat a good indica, then take 3-5 wheels of glycine, eat a pack or two of ascorbic acid, a chocolate bar, pour tea with lemon(this can all help to remove psychoses and hallucinations from the herb that spice consists of if it is not a simple chamomile from the pharmacy, but a multi-colored one.) and when you already do all this and let the indica go, you can divide a bag of spice 3g into 60 parts(and this will be the maximum dosage) smoke spice.
I'm not campaigning, but if you know more, your life is easier.
In fact, it is quite difficult to explain absolutely clearly why this or that effect of cannabinoids occurs to a certain extent, since even the function of cannabinoid receptors is not particularly clear. Here, the effects of opiates and psychostimulants are quite straightforward and narrow, and you can easily explain each effect of amphetamine or heroin, guided not by guesses, but by facts.
So far, we can only say for sure about the emergence of gluttony from grass and synth. cannabinoids. The function of the most natural action of endogenous anandamide and its corresponding cannabinoid receptors is responsible for this. In addition to the fact that the release of the endogenous cannabinoid anandamide accompanies the consumption of sugar and delicious food, motivating us to consume them more than tasteless food, cannabinoids increase the activity of nerve cells, which they spend a lot of energy – and we get energy from food, so a person who smokes spice or grass, you need to stupidly eat more food to keep the brain “in order”. And this is the reason why many plankers, although they eat more, still do not gain much weight.
I'm afraid that for a detailed answer to this question, we can all be locked up in the basements of Roskomnadzor and tortured, but, as they say:”Who does not take risks, he does not drink champagne.” Let's start from afar.
Evolutionarily, the biochemical system of the human brain, which regulates the vast majority of all processes in our body, is an open system. What does it mean? This means that exogenous chemicals, under certain conditions, can “integrate” into the biochemistry of our brain and “replace” their “endogenous counterparts” for a certain time (it's easier to read more about endogenous and exogenous substances in Wikipedia or on resources dedicated to biochemistry, otherwise we will pass the entire chemistry course). Thus, when, for example, we drink tea, caffeine, which is the main active alkaloid of this wonderful drink, enters the brain. Since caffeine is structurally similar to our “native”, endogenous substance, adenosine, it gets a great opportunity to bind to the same receptors (adenosine) with which adenosine binds. And this is where the fun begins: the effect of coefin is exactly the opposite of that of adenosine, which inhibits arousal processes in the brain. This explains the invigorating effect of caffeine.
The mechanism of action of any narcotic substance (and caffeine, like nicotine, alcohol, and many other “legal” substances, is a drug) is described in a similar way.
The active ingredients of marijuana belong to the class of cannabinoids. In the case of “natural” marijuana products (starting with hashish and ending with amber oil), the psychoactive effect is caused by two main components:: CBD (cannabidiol) and THC (tetrahydrocannabinol), as well as some other, weaker ones that can be ignored (cannabinol, cannabinolic acid derivatives, etc.)
These substances are agonists of the CB1 and CB2 cannabinoid receptors, the endogenous agonist of which is anandamide and its derivatives (yes, there are a whole bunch of endogenous cannabinoids in the ogranizme of any of us, such things), which causes the effects of natural marijuana. Surely you know what effects I'm talking about right now?
Wait, but the effects can vary, for example, hashish is more sedative, and inflorescences are more psychoactive. This, in turn, is due to the proportions of cannabinoids in our, ahem, product — the more THC, the more active the product, the more CBD — the more sedative it is.
And what about”spice”? This is a topic for a full-fledged research paper. After the first category of artificial cannabinoids was discovered (sorry, look for it yourself), which was just as quickly and successfully added to the list of banned substances, smart Chinese and home-grown chemists quickly realized that the synthesis of such compounds is very simple. To date, there are more than a hundred known (and already banned) synthetic cannabinoids alone, but the industry does not stop there. Here you will find naphthoylindoles, phenylacetylindoles, cyclohexylphenols, and dibenzopyrans — and these are only the studied groups of synthetic cannabinoids.
Their action is based on the same principle as the action of natural cannabinoids, namely, on interaction with our cannabinoid CB1 and CB2 receptors. But unlike the same THC, synthetic cannabinoids (for example, HU-210) are often non-selective agonists, hundreds of times more effective than THC. All cases of, so to speak, temporary mental confusion, involuntary exits out of the window and other fun acts committed under “spice” are due to the wildest, simply unrealistic overdose — you will never smoke as much marijuana (or hashish) in your life as you need to achieve the same level of prostration that can be achieved by puffing a little spice.
My advice to you: drink tea, smoke cigarettes, and read about the terrible consequences of all sorts of spices on the Internet, do not check all this for yourself.